NMN infusion therapy

It is the next-generation anti-aging therapy, known as NMN (Nicotinamide Mononucleotide) infusion, that has been discovered to restore youthfulness in research conducted by Harvard Medical School. The groundbreaking research conducted at Harvard Medical School has shown promising results in reversing age-related decline and promoting various health benefits. NMN infusion has demonstrated the potential to improve mitochondrial function, enhance metabolism, and increase cellular resilience. It has also shown promising effects in promoting cognitive function, cardiovascular health, and overall vitality.

NMN infusion in addressing age-related conditions and promoting overall well-being.

What is NMN

NMN, short for Nicotinamide Mononucleotide, is a substance similar to vitamin that plays a crucial role in the body's natural repair and regeneration processes. It is naturally produced in the human body and is involved in repairing organs and tissues. However, the production of NMN decreases with age, leading to the aging of physical and cognitive functions.

Recent research has revealed the potential benefits of NMN supplementation, including improved physical function and enhanced cognitive abilities. These findings have garnered significant attention worldwide, with numerous studies exploring the effects of NMN and its potential applications in promoting overall well-being.

Recommended for individuals with these concerns:

  • Feeling easily fatigued lately
  • Experiencing decreased concentration
  • Having trouble falling asleep or experiencing light sleep
  • Concerned about blemishes, wrinkles, sagging, etc.
  • Noticing a loss of skin firmness and radiance
  • Experiencing a lack of hair volume, thinning, and weakening, etc.

Features of NMN

What is sirtuin (longevity) gene activation by NMN infusion?

Everyone desires to remain youthful and healthy for as long as possible. However, as we age, our skin and physical vitality naturally decline, aligning with our advancing years. But what exactly causes aging? There exists a class of genes deeply involved in human aging and lifespan, known as sirtuin genes.

Activation of these genes can enhance various bodily functions, including skin cell regeneration, physical endurance, and fatigue management, ultimately leading to rejuvenation. NMN infusion serves the purpose of activating these sirtuin genes, enabling individuals to maintain their youthfulness and embrace a healthy lifestyle.


図解:サーチュインファミリーの遺伝子系統樹 実験医学Vol.31 No.20(増刊)P46からの引用

Activating the Sirtuin Gene with NMN

The rejuvenating compound NMN is absorbed into the body and subsequently converted into a substance called NAD+ that reaches every corner of the body.

NAD+ is present in the bodies of all living organisms and plays a crucial role in maintaining youthfulness and overall health. However, its levels naturally decline, reaching a peak in the late teens and gradually diminishing thereafter. By the time one reaches their 40s, NAD+ levels may have decreased by half, resulting in a loss of youthful vitality.

To address this, replenishing NMN, which serves as the precursor to NAD+, proves to be an effective method for increasing NAD+ concentrations within the body.


Harvard Medical School NMN Study

NMN was administered to mice at 22 months of age, which is equivalent to 60 years in humans. After just one week, they exhibited muscle mass comparable to that of 6-month-old mice, which is equivalent to 20 years in humans. In other words, they achieved a remarkable rejuvenation of 40 years in just a short period of one week.

No negative effects of NMN have been discovered thus far. On the contrary, it has been found to have protective effects on eye diseases, hearing loss, liver, and heart. Furthermore, when administered to mice with liver cancer, it resulted in the disappearance of tumors. These facts have been confirmed by research laboratories worldwide.

22 months old 60 years old in human terms ). 1 week later. 6 months old 20 years old in human terms )

How to Obtain NMN through Diet?

There are certain foods that contain small amounts of NMN, such as green soybeans, broccoli, cucumbers, and avocados. However, the content of NMN in these foods is minimal.

For example, to consume 100 mg of NMN per day from broccoli, approximately 40 kg (around 2,000 bunches) of broccoli would be required. Similarly, consuming 126 avocados would be necessary to reach the same amount of NMN.

To efficiently incorporate NMN into the body, infusion is a recommended method.

図解:NMN100mg=40 kg of broccoli(about 2000 rooms)

About the treatment:

  • Treatment duration: 15-30 minutes
  • Treatment interval: Once every 2-3 weeks

Side effects/Risks

During the infusion therapy, you may experience the following mild discomfort: mild pain, redness, subcutaneous bleeding, swelling, warmth sensation, pigmentation, and rare cases of infection at the infusion site. Additionally, there is a very small risk of nerve damage, vagal reflex, allergic reactions, or anaphylactic shock.

Please note that these side effects and contraindications are relatively rare. However, we still recommend consulting with your doctor for a detailed assessment and consultation before undergoing the treatment.


  • Pregnant and breastfeeding individuals are advised not to undergo this treatment.

Declaration of Unapproved Drugs and Sources of Acquisition

The unapproved drugs used in this treatment have not obtained approval under the Pharmaceutical and Medical Device Act. They are dispensed within the clinic (partially outsourced) in compliance with legal regulations. In Japan, the use of unapproved drugs is permitted under the responsibility of the physician.

Indication of Availability of Approved Domestic Drugs

There are no other domestically approved drugs available with the same capabilities for this treatment.

Declaration of Safety Information in Other Countries

There are no countries in major Western nations where it has been approved. However, clinical trials (double-blind randomized trials) have been initiated, including at the University of Washington School of Medicine.

In Japan, clinical trials have been conducted by a group from Keio University School of Medicine, concluding that it can be safely administered to humans.

At present, there have been no reports of serious side effects.








こちらの施術内容ページは医学的・専門的な内容の為、当院院長の三島 雅辰監修の元作成しております。



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